A Systematic Review on the Role of Intermuscular Adipose Tissue in Metabolic (IMAT) Changes: Interconnecting to Obesity, Aging, and Exercise

• Posted by: Admin
• Rabu, 14 Juni 2023
• Has been read 254 time(s)

Researchers from the Faculty of Medicine, Udayana University and Prof. Ngoerah Hospital, led by Dr. dr. I Gusti Putu Suka Aryana, Sp.PD-KGer, FINASIM succeeded in publishing the results of a systematic review in the journal touchREVIEWS in Endocrinology with an article entitled "The Important Role of Intermuscular Adipose Tissue on Metabolic Changes Interconnecting Obesity, Aging and Exercise: A Systematic Review"

With increasing progress in the health sector, life expectancy has also increased, in line with co-morbidities such as heart and metabolic diseases. Where as you get older, the function of the organs decreases and starting from 40 years, muscle mass decreases and is replaced by fat. One of the fats of concern is ectopic, IMAT is a form of ectopic fat, less than five percent of the total. IMAT is a new term and terminology found among muscles and within muscles that is very different from subcutaneous adipose tissue. These fats are associated with metabolic syndrome and the occurrence of heart disease. Syndromes include high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels.

Some of the latest conjectures say that IMAT is directly related to fatty blood vessels, diabetes and heart disease. Based on a literature review of 1247 found six studies that examined IMAT, stating that IMAT is significantly related to the risk of metabolic syndrome and heart disease. Two clinical trials state that IMAT can be reduced by doing a combination of aerobic and resistance type exercise.

Thus the authors hope that a screening test can be carried out by measuring IMAT levels in at-risk populations. So as early as possible can take preventive steps. Articles can be accessed at the following link http://dx.doi.org/10.17925/EE.2023.19.1.54