Isometric Exercise Approach Has Potential to be Early Therapy for Sports Injuries

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• Senin, 19 Mei 2025
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Isometric Exercise Approach Has Potential to be Early Therapy for Sports Injuries

Located in the Postgraduate Hall, 3rd Floor of the Postgraduate Building, Udayana University, the Doctoral Study Program in Medical Science, Faculty of Medicine, Udayana University held an open Doctoral Promotion examination with the candidate for promovendus, Moh. Ali Imron, S.Sos, M.Fis., with the dissertation title "Differences in MicroRNA-155, Interleukin-6, Cyclooxygenase-2 Enzyme and Pain in Sports Injuries Given Isometric Muscle Contraction and Isotonic Muscle Contraction Exercise Interventions with Progressive Continuous Doses.". (5/16/2025)

Exercise has health benefits but also has risks, one of which is muscle injury. Early injury management is very important to achieve rapid recovery. Two approaches are the RICE principle (rest, ice, compression and elevation) and PEACE ((protect, elevate, avoid anti-inflammatory drugs, compression, educate) and LOVE (load, optimism, vascularisation, exercise). There are two types of muscle contractions in exercise, namely isometric and isotonic. This study aims to see the difference between isometric muscle contraction exercises and isotonic muscle contractions in muscle injury seen from the expression of miRNA-155, Interleukin-6, cox2 enzyme and pain

The research method used is true experimental with pre and post control group design where randomization is carried out on sample division. The sampling technique used is purposive sampling, namely taking samples from the population by setting inclusion and exclusion criteria. The number of samples in this study was 21 people who were divided into 3 groups with 7 people each.

The results of the analysis showed that there were differences in miRNA-155 expression and pain in the three groups (p < 0.05). While the results of the analysis showed that there was no difference (p> 0.05) in IL-6 and Cox-2 enzyme levels in all three groups.

It can be concluded that there is a difference in miRNA-155 expression in sports injuries given isometric muscle contraction training compared to isotonic muscle contraction training and the control group. Meanwhile, in the levels of IL-6 and Cox-2 Enzyme, the results showed no significant difference in sports injuries given isometric muscle contraction training compared to isotonic muscle contraction training and the control group. So that isometric muscle contraction training with a measured dose is good to do at the beginning of the injury to reduce pain and isotonic contraction training with a measured dose is better done as a continuation of training in sports injuries to stimulate tissue regeneration.

This examination was led by the Dean of the Faculty of Medicine, Udayan University, Prof. Dr. dr. Komang Januartha Putra Pinatih, M.Kes., with the following examiner team:

1. Prof. Dr. dr. I Putu Gede Adiatmika, M.Kes (Promoter)

2. Prof. Dr. dr. I Made Jawi, M.Kes (Co-promoter I)

3. Prof. Dr. dr. Susy Purnawati, M.KK (Co-promoter II)

4. Prof. Dr. Dr. Pamudji Utomo, Sp.OT

5. Prof. Dr. Dr. Cokorda Bagus Jaya Lesmana, S.Ked., Sp.KJ(K), MARS

6.Dr. Ni Wayan Tianing, S.Sc., M.Kes

7.Dr. Dr. Agung Wiwiek Indrayani, S.Ked., M.Kes

8.Dr. Dr. I Made Muliarta, S.Ked., M.Kes

9.Dr. Dr. I Gusti Lanang Sidiartha, Sp.A(K)

10.Dr. Dr. I Wayan Suranadi, Sp.AnTI,Subsp.T.I.(K)

By academic invitation:

1.Dr. Dr. I Gusti Ayu Artini, S.Ked., M.Sc.

2.Dr. NS. Ni Ketut Guru Prapti, S.Kep., MNS

3.Dr. Dr. I Kadek Swastika, S.Ked., M.Kes

4. Dr. dr. Putu Adi Suputra, S.Ked

5. Dr.Ns. Kadek Cahya Utami, S.Kep., M.Kep

In this exam, Dr. Moh. Ali Imron, S.Sos, M.Fis., was declared to have passed as the 459th Doctoral Graduate of the Doctoral Program in Medical Sciences, Faculty of Medicine, Udayana University with the predicate Very Satisfactory

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