Dr. Ari Andayani, Sp.M(K) Receives Doctoral Degree for Researching the Potential of Purple Sweet Potato Tubers Extract in Reducing Retinal Damage Due to High Blood Sugar Levels

• Posted by: Admin
• Selasa, 25 Januari 2022
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Tuesday, January 25, 2022.

A hybrid Doctoral Promotion was conducted on behalf of dr. Ari Andayani, Sp.M(K) with the dissertation title "The Effect of Giving Purple Sweet Potato Extract Compared to Blueberries on Retinal VEGF mRNA Expression, Retina COX-2 Expression, and Blood Glutathione Levels in Hyperglycemic Model Mice" at Prof.dr. I Goesti Ngoerah Gde Ngoerah.

Long-term hyperglycemia can harm the retina as well as other parts of the eye. Hyperglycemia can harm the retina's microvascular system by causing an increase in angiogenesis factors, inflammation, and oxidative stress. The goal of this study is to see how purple sweet potato tuber extract compares to blueberries in terms of angiogenesis, inflammation, and oxidative stress in hyperglycemic rats.

The study's unique feature is that it directly examines the role of purple sweet potato tubers and blueberries in reducing oxidative stress, inflammatory factors, and angiogenesis factors in hyperglycemic circumstances. According to this study, purple sweet potato tubers have the same anti-oxidant properties as blueberries and can help to reduce inflammation. Purple sweet potato tubers can be used to substitute blueberries, which are more difficult to obtain and more expensive, because purple sweet potato tubers are easier to produce and cheaper in Indonesia, particularly in Bali.

This study shows that giving purple sweet potato tubers to hyperglycemic mice reduces inflammation, angiogenesis, and oxidative stress by raising glutathione levels and reducing COX-2 levels. In terms of raising glutathione levels and lowering COX-2 expression, purple sweet potato tubers had the same effect as blueberry extract.

The Doctoral Promotion was led this time by Dr. dr. Komang Januartha Putra Pinatih, M.Kes, Dean of the Unud Medical Faculty, with a team of examiners:

1. Prof. Dr. dr. Sri Maliawan, Sp.BS (K), FICS (Promoter)

2. Prof. drh. I Nyoman Mantik Astawa, Ph.D (Copromotor I)

3. Prof.Dr.Ir.Ida Bagus Putra Manuaba, M.Phil (Copromotor II)

4. Prof. Dr. dr. I Made Bakta, Sp.PD-KHOM

5. Prof. dr. Ni Ketut Niti Susila,Sp.M(K)

6. Prof. Dr.dr. I Made Jawi, M.Kes

7. Dr. dr. Tjok Gde Agung Senapathi, Sp.An.,KAR

8. Dr. dr. Made Ratna Saraswati, Sp.PD,KEMD.,FINASIM

9. Dr. dr. Cokorda Bagus Jaya Lesmana, S.Ked .,Sp.KJ(K),MARS

10. Dr. dr. I Wayan Niryana, M.Kes.,Sp.BS(K)

Academic invitations are as follows :

1. Dr.rer.nat.dr.Ni Nyoman Ayu Dewi,M.Si

2. Dr. dr. Anak Agung Mas Putrawati Triningrat, Sp.M(K)

3. Dr. dr. Putu Yuliawati, Sp.M(K)

4. Dr. dr. Ariesanti Tri Handayani, Sp.M (K)

5. Dr. dr. I Wayan Eka Sutyawan, Sp. M (K)

Dr. dr. Ari Andayani, Sp.M(K) received the predicate VERY SATISFACTORY as the 336th Graduate of the Doctoral Study Program of Medical Sciences, Faculty of Medicine, Udayana University.

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